
E109: 2022 Bestie Awards Live from Twitter HQ
TL;DR
- The All-In podcast besties convened at Twitter HQ to hand out their annual Bestie Awards recognizing the biggest winners, losers, and surprises across politics, business, science, and culture in 2022
- Major political winners included those who benefited from the midterm elections, while losers encompassed figures diminished by election results and various scandals throughout the year
- Business awards highlighted successful executives and companies alongside those that experienced significant downturns, with particular focus on leadership changes and market performance
- Scientific breakthroughs in CRISPR gene editing and cancer treatments were recognized as major achievements, contrasting with overhyped trends that failed to deliver
- The panel debated the best and worst trends of 2022, from technological innovations to cultural phenomena, offering candid assessments of what worked and what flopped
- The awards concluded with the Rudy Giuliani Award for Self-Immolation, recognizing the year's most spectacular public downfall and embarrassment
Episode Recap
In this special live episode recorded at Twitter headquarters, Andrew Huberman joined the All-In podcast besties for their annual 2022 Bestie Awards ceremony. The panel consisting of Chamath Palihapitiya, Jason Calacanis, David Sacks, and David Friedberg spent over two hours debating and voting on the biggest winners, losers, surprises, and notable figures across politics, business, science, technology, and culture throughout 2022.
The discussion began with politics, where the panel evaluated which figures and parties benefited most from the year's midterm elections and other political developments. The conversation then shifted to identifying the biggest political losers, examining scandals and career setbacks that defined 2022. A particularly engaging segment focused on the most surprising political moments of the year, with the panel debating unexpected turns of events that captured national attention.
The business segment proved equally robust, with the besties nominating and discussing the biggest winners in the corporate world, recognizing successful CEOs and companies that thrived despite economic headwinds. They contrasted these successes with major business losers, examining companies and executives that faced significant challenges, setbacks, or reputational damage. The business surprise category highlighted unexpected corporate developments, including dramatic leadership changes like Bob Iger's return to Disney and Elon Musk's acquisition of Twitter.
Science and technology received considerable attention, with the panel unanimously recognizing breakthroughs in CRISPR gene editing technology as a major scientific achievement with profound implications for treating cancer and genetic diseases. They also identified various flash-in-the-pan trends that captured attention but ultimately failed to deliver meaningful impact or sustainability.
The awards continued with specific categories for the best CEO of the year, whose leadership and vision shaped their organization's direction and success. The panel debated top investors who demonstrated exceptional judgment and returns, contrasting them with the worst investors whose decisions proved costly or misguided. A turnaround story award recognized companies or executives who reversed decline and achieved remarkable comebacks.
The most provocative segments included the worst human being award and the most loathsome company category, where the panel offered sharp critiques and controversial opinions. These awards sparked debate and reflected the besties' willingness to make bold, sometimes contentious judgments about public figures and institutions.
The conversation also covered best new technologies emerging in 2022, analyzing innovations that showed genuine promise and potential to reshape industries. The panel identified the best and worst trends of the year, ranging from cultural phenomena to business practices, offering nuanced perspectives on what succeeded and what failed. A discussion of favorite media highlighted outstanding books, podcasts, and other content that deserved recognition.
The episode concluded with the Rudy Giuliani Award for Self-Immolation, recognizing the year's most spectacular public downfall. This irreverent award highlighted individuals whose reputational damage or public embarrassment reached particularly dramatic proportions, providing a fitting and humorous end to the awards ceremony.
Key Moments
Notable Quotes
“The 2022 Bestie Awards represent our honest assessment of who won, who lost, and what surprised us most this year”
“CRISPR gene editing technology represents a genuine scientific breakthrough that could transform how we treat cancer and genetic diseases”
“We need to recognize both the spectacular successes and equally spectacular failures that defined 2022”
“The best trends are those that actually deliver value and sustainability, not just hype and temporary attention”
“This year showed us that leadership transitions and corporate drama can dramatically reshape entire industries and markets”


